MOBG101 General and Cell Biology
Course Description: The aim of this course is to present the basic concepts of living organisms, and biological structures. This course will also provide understanding to the cell biology including organelles, cell communication and cytoskeleton. It will also provide brief introduction to nucleic acids.
Examinations: Midterm and final

CHEM104 Chemistry for Biological Sciences
Course Description: This course will provide an understanding of chemical concepts and principles, covering atomic structure and periodic table, chemical bonds and molecular configurations, states of matter, chemical thermodynamics, solutions, oxidation‒reduction reactions and transformation of chemical energy, electrochemistry.
Examinations: Midterm and final

PHY101 Introduction to Physics
Course Description: This course will provide a solid grounding in physical concepts and principles, covering kinematics and dynamics, fluids, elasticity, wave motion, sound, ideal gases, heat and thermodynamics.
Examinations: Midterm and final

MOBG102 IT and Numeracy Skills for Molecular Biologist
Course Description: This course will focus on enabling students to develop essential skills in IT literacy including use of different programs for molecular biologists and develop students to assess numeracy skills and ability to evaluate experiment data.
Examinations: Midterm and final

MOBG103 Academic English and Writing Skills
Course Description: This course will focus on the mastery of specific medical vocabulary and idioms, and improvement in the ability to communicate in English in a hospital or clinical setting.
Examinations: Midterm and final

AIT 101 Atatürk İlkeleri ve İnkilap Tarihi
Course Description: This course will focus on the political, economical and cultural problems that were being faced during the break down of Ottoman Empire. Establishment of the Turkish Republic by Mustafa Kemal Atatürk will also be covered in this course.
Examinations: TBA

TUR 101 Türkçe I
Course Description: This course will focus on the Turkish language and composition.
Examinations: TBA

Molecular Cell Biology
Course Description: This course will provide an understanding of the structure and the function of nucleic acids. It will also cover gene expression, cell divisions and recombination. It will provide an introduction to germ cell development and fertilisation.
Examinations: Midterm and final

MOBG105 Basic Principles of Genetics
Course Description: This course will provide an understanding of mutations and polymorphisms, Mendelian genetics, non-Mendelian genetics, biochemical and immunogenetics, cancer genetics and population genetics.
Examinations: Midterm and final

MOBG106 Organic Chemistry
Course Description: This course will provide an understanding of the fundamental principles of organic chemistry, including nomenclature, structure, bonding, and the basic principles of stereochemistry. Important reactions related to the common functional groups will be covered with emphasis on reaction mechanisms.
Examinations: Midterm and final

MOBG107 Biostatistics
Course Description: This course will focus on the application of statistical theory to real-world issues, the practice of designing and conducting biomedical experiments and clinical trials, and the study of related computational algorithms and display of data.
Examinations: Midterm and final

MOBG201 Chromosome Dynamics
Course Description: This course will consider the fundamental aspects of chromosome structure and function, with emphasis on genome organisation, inherited disorders, and chromosome aberrations.
Examinations: Midterm and final

MOBG202 Genes and Inheritance
Course Description: This course will provide an understanding of basic genetic processes. Inheritance patterns of single-gene traits, pedigree construction, chromosome aberrations, and the multifactorial basis underlying many common traits will be explored.
Examinations: Midterm and final

MOBG203 Anatomy and Physiology
Course Description: This course will consider the principal functions of the human gastro-intestinal tract and the renal system, explaining how these systems are affected by diseases.
Examinations: Midterm and final

MOBG204 Microbiology
Course Description: This course will focus on the study of some major groups of bacteria and parasites of importance in human infection and on the understanding of the key concepts used in investigating and diagnosing infections in the laboratory.
Examinations: Midterm and final

MOBG205 Biochemistry
Course Description: This course will provide an understanding of the structure and function of nucleic acids, proteins, lipids, and carbohydrates, the relationships between them, and their synthesis and breakdown. Further topics will include the processes by which the central biochemical pathways make energy, and build new cells from raw materials. Basic concepts in metabolism and metabolic regulation will be introduced to show the role of biochemistry in human health and disease.
Examinations: Midterm and final

MOBG206 Biotechnology Techniques
Course Description: This course will provide an overview of the theory, principles and practical applications of a number of techniques used in the study of biomolecules, especially nucleic acids and proteins.
Examinations: Midterm and final

MOBG207 Human Genetics and Genomics
Course Description: This course will focus human genetic variation, genomic technology and the structure and function of the human genome. This course will also involve different types of DNA damage, the cellular defence mechanisms that preserve genetic integrity and the major repair mechanisms used by human cells to correct different types.
Examinations: Midterm and final

MOBG208 Embryology, Developmental Genetics and Teratology
Course Description: This course will consider the fundamental genetics of developmental events and concepts, covering techniques and concepts in embryology, pattern formation in organisms, genetics of gamete formation, sex determination and dosage compensation, and teratology.
Examinations: Midterm and final

MOBG209 Biophysics
Course Description: This course explores the principles of structure formation of biomacromolecules, presenting physical methods for the measurement of molecular forces and molecular structure. It will also deliver insight into membrane physics and transport phenomena.
Books: 1) An Introduction Biophysics, 2E, Roland Graser, 2012 2) Biophysics, William Bialeck, 2012
Examinations: Midterm and final

MOBG210 Introduction to Pharmacology
Course Description: This course will provide a firm foundation in the principles underlying pharmacology and toxicology, including the nature of drug targets, their interaction and response, the fate of drugs within the body, toxicity classification and testing, poisons and antidotes, adverse drug reactions, selective toxicity, drug discovery and development.
Examinations: Midterm and final

MOBG301 Medical Genetics
Course Description: This course will provide the basic principles in medical genetics and the relation between the current knowledge of genetics and clinical applications. This course will further focus on the clinical relevance of the genome structure, mutations, screening, Mendelian and polygenic inheritance and risk assessments of inherited disorders.
Examinations: Midterm and final

MOBG302 Gene Regulation and Epigenetics
Course Description: This course will provide an overview of gene expression and regulation in eukaryotes, covering different RNA polymerases, mechanisms of RNA processing, general and specific transcription factors which interact to regulate gene expression. It will also give a general overview on basic mechanisms of epigenetics and it relevance for human biology.
Examinations: Midterm and final

MOBG303 Population Genetics and Genetic Epidemiology
Course Description: This course will provide an understanding of the processes affecting the distribution of genetic variation in populations of organisms, through space and time. The Hardy-Weinberg principle, gene flow, genetic drift, recombination and linkage disequilibrium, natural selection, the effect of mating systems on diversity, and the neutral theory of evolution will also be covered. How genetic factors contribute to health and disease in families and populations, and how genes interplay with environmental factors will also be covered in this course.

MOBG304 Bioinformatics
Course Description: This course will focus on the use of online public databases and software to extract, analyse and interpret nucleic acid and protein sequences and to model the structures of RNA and protein sequences.
Examinations: Midterm and final

MOBG305 Neurogenetics and Endocrine Genetics
Course Description: This course will focus on the genetic analysis of neurological and endocrinological conditions and what we can learn about their causes by investigation of the genes identified.
Examinations: Midterm and final

MOBG306 Evolutionary Genetics
Course Description: This course will outline the process of evolution, by looking at studies on genetic variation in populations together with theoretical examination of how genes behave in populations. The role of natural selection in evolution will be probed using empirical evidence and theoretical examinations of evolution in action.
Examinations: Midterm and final

MOBG307 Protein Structure and Function
Course Description: This course will provide an understanding of the structural organisation of proteins and its relevance to protein function and an awareness of the biophysical methods available to study protein structure.
Examinations: Midterm and final

MOBG308 Reproductive and Regenerative Medicine
Course Description: This course will explore recent discoveries about how reproduction is controlled, how it is affected by diseases and how reproductive processes can be manipulated by medical and pharmacological intervention.
Examinations: Midterm and final

MOBG402 Cancer Genetics
Course Description: This course will consider the genetic mechanisms underlying specific cancer types, discussing how recent genomic studies have led to the identification of genes that play important roles in cancer formation, and outlining how molecular genetics techniques are facilitating rapid advances in this field.
Examinations: Midterm and final

MOBG403 Prenatal Genetic Diagnosis and Genetic Counselling
Course Description: This course will consider genetic indications for prenatal diagnosis, estimation and calculation of recurrence risks, techniques and their indications: conventional cytogenetics; molecular cytogenetics; mutation analysis; biochemical diagnosis; questionable results; mosaicism and chimaerism. It will also provide a foundation in the growing field of genetic counselling, helping students to determine when to suspect hereditary/genetic conditions, recognise the more common inherited conditions in different clinical settings and develop effective communication skills.
Examinations: Midterm and final

MOBG404 Immunogenetics
Course Description: This module will provide an overview of the cellular and molecular basis of the immune response in human health and disease. The structure, function and complex mechanisms of host defence by B- and T-cells will be explored, covering the role of inflammatory mediators, soluble effectors and cellular cytotoxicity in inflammation and immunity.
Books: Immunology, Thao Doan, Roger Melvold, Susan Viselli, Carl Valtenbaug, 2012
Examinations: Midterm and final

MOBG405 Academic English and Writing I
Course Description: This course will provide information that is essential in writing scientific reports and articles.
Books: Writing Scientific Research Articles: Strategy and Steps, Margaret Cargill , Patrick O'Connor
Examination: Midterm and final

MOBG407 Bioethics
Course Description: This course will examine some of the ethical issues that have arisen recently in the biological sciences, concentrating on the areas of genetic engineering in microbes, plants and animals, environmental conservation priorities, human personhood and its origins, cloning and stem-cell technologies, genetic testing, and gene therapy.
Examinations: Midterm and final

MOBG408 Genetic and Tissue Engineering
Course Description: This course will provide the principles underlying strategies for employing selected cells, biomaterial scaffolds, soluble regulators or their genes, and mechanical loading and culture conditions, for the regeneration of tissues and organs in vitro and in vivo are addressed. Differentiated cell types and stem cells will be compared and will be contrasted for this application, as are natural and synthetic scaffolds. The rationale for employing selected growth factors is covered and the techniques for incorporating their genes into the scaffolds will be examined. Discussion also addresses the influence of environmental factors including mechanical loading and culture conditions (e.g., static versus dynamic). Methods for fabricating tissue-engineered products and devices for implantation will be taught. Examples of tissue engineering-based procedures currently employed clinically will be analyzed as case studies.
Examinations: Midterm and final

MOBG409 Academic English and Writing II
Course Description: This course will provide information that is essential in writing scientific reports and articles.
Examination: Midterm and final

MOBG501 Enzymology
Course Description: This course will explain the molecular basis of the often complex catalytic mechanisms of enzymes in biological systems, focusing particularly on their relevance to and applications in medicine. The underlying principles of enzyme catalysis and techniques for the study of enzyme mechanism and structure will be covered.
Examinations: Midterm and final

MOBG502 Virology
Course Description: This course will explain the major virus families, virus structure, steps in viral replication, interaction with cellular signalling pathways, diseases and pathogenesis.
Examinations: Midterm and final

MOBG503 Ageing
Course Description: This course will survey the biology of ageing, covering evolutionary and mechanistic theories of ageing, the new model organism genetics of lifespan, methods in ageing research, cellular senescence, telomeres and cancer, prospects for treatments for ageing.
Examinations: Midterm and final

MOBG504 Nutrigenetics, Nutrigenomics and Persolised Nutrition
Course Description: This course will focus on understanding of biochemistry, nutrition physiology, and basic knowledge of genetics /molecular biology. The objectives of the module will include knowledge of nutrient relevant pathways of metabolism and cellular signalling cascades, regulation of metabolism pathways in different levels (molecular, cellular, level of organ, organism) of biological integrity, basics of genetic variations, constitutive databases and their appliances.
Examinations: Midterm and final

MOBG505 Behavioural Genetics
Course Description: This course will provide a fundamental underpinning for human behavioural genetics, looking at putative genetic factors in human behavioural dimensions.
Examinations: Midterm and final

MOBG506 Forensic Genetics
Course Description: This course will explore history of forensic DNA analysis, mini-satellite DNA and short tandem repeats (STRs), DNA sequences as unique human identifiers, DNA extraction and PCR; STR analysis, ethics of DNA and DNA databases, overview of the molecular genetics and use of polymorphisms (mitochondrial DNA, single nucleotide polymorphisms (SNPs) and Y-STR profiling) in human identification.
Books: Forensic DNA Typing: Biology, Technology, and Genetics of STR Markers, John M. Butler, 2005
Examinations: Midterm and final

MOBG507 IT and Numeracy Skills in Advanced Molecular Biology
Course Description: This course will provide the use of programs, such as MatLab, that are essential in molecular biology.
Books: 1) Animal Cell Culture and Technology: The Basics, Michael Butler, 2003. 2) Mammalian Cell Cultures for Biologics Manufacturing (Advances in Biochemical Engineering/Biotechnology), Weichang Zhou, Anne Kantardjieff, 2014.
Examinations: Midterm and final

MOBG508 Nanotechnology and modelling in biological systems
Course Description: This course will explore the basics of the quantum mechanics and molecular mechanics methods, with emphasis on modelling the structures and reactions of small molecules of biological importance using quantum methods and studying the structures and dynamics of biological macromolecules using molecular dynamics simulations.
Books: 1) Modeling Biological Systems: Principles and Applications, James W. Haefner, 2005. 2) Nucleic Acid Nanotechnology (Nucleic Acids and Molecular Biology), Jorgen Kjems, Elena Ferapontova, 2013
Examinations: Midterm and final

MOBG509 Gene Therapy
Course Description: This course will provide an overview of gene therapy, emphasising the clinical history, the types of diseases that could benefit the most, and ethical issues. Some of the major gene transfer vector systems will be covered in detail, highlighting advances in this rapidly developing field.
Examinations: Midterm and final

MOBG510 Stem Cell Biology
Course Description: This course will provide an in-depth account of stem cell biology, covering molecular and genetic control of cell fate specification and differentiation, stem cell niches, adult, embryonic and cancer stem cells and induced pluripotent cells, using stem cells for therapy, ethical use of stem cell therapy and recent research issues.
Examinations: Midterm and final

MOBG511 Pharmacogenetics and Personalised Medicine
Course Description: This course will provide an overview of the molecular basis of pharmacogenetics, helping students to understand the implications of genetic variability on pharmacokinetics and pharmacodynamics, as well as other aspects such as adverse drug reactions. It will focus on the genetic determinants of drug response at the single gene level, and its impact on pharmaceuticals, therapeutics, and clinical practice.
Examinations: Midterm and final